Most magnesium compounds available on the market have low bioavailability in the cognitive tissue because they cannot cross the blood brain barrier easily. Magtein is better absorbed than other magnesium compounds and has clinical research to show that it is highly effective in crossing the blood brain barrier unlike other magnesium agents. Magtein is well tolerated by the GI tract, unlike other magnesium compounds which can cause stomach upset and diarrhea. Clinical studies show that Magtein increases the number and density of synapses in the brain, which correlates with improved cognition.