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Description
This high potency combination of CoQ10 and the omega-3 fatty acids EPA/DHA provides cardiovascular and cognitive benefit through multiple distinct and overlapping pathways. Both CoQ10 and EPA/DHA have been shown to improve endothelial function, especially among populations at risk for atherosclerosis (elevated BMI, metabolic syndrome, smoking, hyperlipidemia), with clinically significant hypotensive and anti-atherogenic effects.1-5
CoQ10 has an instrumental role in oxidative phosphorylation and mitochondrial bioenergetics, critical to neuronal health and preventing the mitochondrial dysfunction that underlies numerous chronic diseases, including neurodegenerative disease.6 Additionally, recent data highlights CoQ10’s emerging role in reducing inflammation and insulin resistance, which are potent contributors to impaired cognitive function.7-9 Meta-analysis of randomized trials has shown CoQ10 and EPA/DHA supplementation reduces key biomarkers of inflammation, including C-reactive protein, TNF-alpha, and IL-6.10-12 CoQ10 serum levels have also been associated with neurological outcomes following ischemic stroke, as well as the risk for disabling dementia.13,14
OptiMega-3 Q10 also provides high dose pharmaceutical grade EPA/DHA, shown to reduce many cardiovascular risk factors and improve vascular function, with controlled clinical trials demonstrating a reduced rate of cardiovascular and coronary events, particularly in persons at high risk.15-19 Omega-3 fatty acids have been associated with reduced myocardial infarction, as well as stroke, with supplementation mitigating adverse changes to the left ventricle, myocardial fibrosis, and systemic inflammation following a myocardial infarction.20-23 EPA/DHA support cognitive function through multiple mechanisms, as both are indispensable to neuronal membranes, with lower levels found to be not only a marker for neurological disease but also a risk factor for cognitive impairment.24,25
